Why are missing quality of life data a problem in clinical trials of cancer therapy?

@article{Fairclough1998WhyAM,
  title={Why are missing quality of life data a problem in clinical trials of cancer therapy?},
  author={Diane Lynn Fairclough and Harriet F. Peterson and V{\'i}ctor E Chiang Chang},
  journal={Statistics in medicine},
  year={1998},
  volume={17 5-7},
  pages={
          667-77
        }
}
Assessment of health related quality of life has become an important endpoint in many cancer clinical trials. Because the participants of these trials often experience disease and treatment related morbidity and mortality, non-random missing assessments are inevitable. Examples are presented from several such trials that illustrate the impact of missing data on the analysis of QOL in these trials. The sensitivity of different analyses depends on the proportion of assessments that are missing… CONTINUE READING
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