Why Polyphenols have Promiscuous Actions? An Investigation by Chemical Bioinformatics.

Abstract

Despite their diverse pharmacological effects, polyphenols are poor for use as drugs, which have been traditionally ascribed to their low bioavailability. However, Baell and co-workers recently proposed that the redox potential of polyphenols also plays an important role in this, because redox reactions bring promiscuous actions on various protein targets… (More)

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