Why Is Initial Bacterial Colonization of the Intestine Important to Infants' and Children's Health?

  title={Why Is Initial Bacterial Colonization of the Intestine Important to Infants' and Children's Health?},
  author={Pearl D Houghteling and W. Walker},
  journal={Journal of Pediatric Gastroenterology and Nutrition},
ABSTRACT Microbial colonization of the infant occurs during a critical time window for immune and gastrointestinal development. Infant colonization sets the stage for the adult microbiome. This review is a broad survey of the factors affecting infant colonization and the downstream effects on gastrointestinal health and disease. Major topics affecting colonization include initial inoculation dependent on birth mode, the impact of breast-feeding, and inside-out modulation of the developing… 
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Microbial contact during pregnancy, intestinal colonization and human disease
The current body of knowledge regarding perinatal microbial contact, initial intestinal colonization and its association with human disease, as well as means of modulating early host–microbe interaction to reduce the risk of disease in the child are described.
Developmental microbial ecology of the neonatal gastrointestinal tract.
In this review, the development of the intestinal microbiota is discussed in terms of initial acquisition and subsequent succession of bacteria in human infants and the advantages of modern molecular ecology techniques that provide sensitive and specific, culture-independent evaluation of the gastrointestinal ecosystem are introduced.
Bacterial colonization of the neonatal gut.
  • M. Pietzak
  • Medicine, Biology
    Journal of pediatric gastroenterology and nutrition
  • 2004
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Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months
The gut microbiota of healthy Canadian infants is characterized and the effects of delivery mode and infant diet as determinants of this essential microbial community in early life are described and advance the understanding of the gut microbiota in healthy infants.