Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values.

@article{Furne2008WholeTH,
  title={Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values.},
  author={Julie K. Furne and Aalia Saeed and Michael D. Levitt},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2008},
  volume={295 5},
  pages={R1479-85}
}
Hydrogen sulfide is gaining acceptance as an endogenously produced modulator of tissue function. The present paradigm of H(2)S (diprotonated, gaseous form of hydrogen sulfide) as a tissue messenger consists of H(2)S being released from the desulfhydration of l-cysteine at a rate sufficient to maintain whole tissue hydrogen sulfide concentrations of 30 microM to >100 microM, and these tissue concentrations serve a messenger function. Utilizing physiological concentrations of l-cysteine and… CONTINUE READING
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