Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions

  title={Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions},
  author={Philippe Rasoanaivo and Colin W. Wright and Merlin L. Willcox and Benjamin Gilbert},
  booktitle={Malaria Journal},
In traditional medicine whole plants or mixtures of plants are used rather than isolated compounds. There is evidence that crude plant extracts often have greater in vitro or/and in vivo antiplasmodial activity than isolated constituents at an equivalent dose. The aim of this paper is to review positive interactions between components of whole plant extracts, which may explain this. Narrative review. There is evidence for several different types of positive interactions between different… CONTINUE READING
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