Whole-lung lavage: a successful treatment for restoring acinar ventilation distribution in primary acquired pulmonary alveolar proteinosis.

@article{Vanderhelst2012WholelungLA,
  title={Whole-lung lavage: a successful treatment for restoring acinar ventilation distribution in primary acquired pulmonary alveolar proteinosis.},
  author={Eef Vanderhelst and Shane Hanon and Sylvia Verbanck and Daniel Schuermans and K Wissing and Francesco Bonella and Walter Vincken},
  journal={Respiration; international review of thoracic diseases},
  year={2012},
  volume={84 1},
  pages={70-4}
}
A 51-year-old active smoker with primary acquired pulmonary alveolar proteinosis (PAP) diagnosed by biopsy and anti-GM-CSF antibodies was treated safely with whole-lung lavage (WLL). This resulted in a rapid improvement of symptoms and arterial blood oxygenation, but not of standard lung function parameters. However, we also performed the multiple-breath… CONTINUE READING