Whole-genome screening for susceptibility genes in multicase families with Behçet's disease.

@article{Karasneh2005WholegenomeSF,
  title={Whole-genome screening for susceptibility genes in multicase families with Behçet's disease.},
  author={Jumana A. Karasneh and Ahmet G{\"u}l and William E. R. Ollier and Alan J Silman and Jane Worthington},
  journal={Arthritis and rheumatism},
  year={2005},
  volume={52 6},
  pages={1836-42}
}
OBJECTIVE Behçet's disease is generally considered to be a multifactorial disease with important genetic and environmental components. A strong association between an HLA class I antigen, HLA-B51, and Behçet's disease has long been known. However, analysis of multicase families has suggested a substantial contribution of non-HLA loci. The aim of this study was to perform a whole-genome linkage analysis for identification of other susceptibility loci for Behçet's disease in multicase families… CONTINUE READING

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