Whole genome phylogeny based on clustered signature string composition

  title={Whole genome phylogeny based on clustered signature string composition},
  author={Xiaomeng Wu and Guohui Lin and Xiu-Feng Wan and Dong Xu},
  journal={2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05)},
Peptide compositions constructed out of whole sets of protein sequences can be used as species signatures for phylogenetic analysis. To account for point mutations, an amino acid substitution model is integrated into the complete composition vectors through a novel peptide clustering algorithm. Such a refined signature is expected to highlight deeper evolutionary relationships among the species and employed into the whole genome phylogenetic analysis to define a new evolutionary distance… CONTINUE READING


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