Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients

@inproceedings{Sigalotti2012WholeGM,
  title={Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients},
  author={Luca Sigalotti and Alessia Covre and Elisabetta Fratta and Giulia Parisi and Paolo Sonego and Francesca Colizzi and Sandra Coral and Samuele Massarut and John Munn Kirkwood and Michele Maio},
  booktitle={Journal of Translational Medicine},
  year={2012}
}
The clinical course of cutaneous melanoma (CM) can differ significantly for patients with identical stages of disease, defined clinico-pathologically, and no molecular markers differentiate patients with such a diverse prognosis. This study aimed to define the prognostic value of whole genome DNA methylation profiles in stage III CM. Genome-wide methylation profiles were evaluated by the Illumina Human Methylation 27 BeadChip assay in short-term neoplastic cell cultures from 45 stage IIIC CM… CONTINUE READING
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