Whole-genome association studies on alcoholism comparing different phenotypes using single-nucleotide polymorphisms and microsatellites

@article{Chen2005WholegenomeAS,
  title={Whole-genome association studies on alcoholism comparing different phenotypes using single-nucleotide polymorphisms and microsatellites},
  author={Liang Chen and Nianjun Liu and Shuang Wang and Cheongeun Oh and Nicholas Carriero and Hongyu Zhao},
  journal={BMC Genetics},
  year={2005},
  volume={6},
  pages={S130 - S130}
}
Alcoholism is a complex disease. As with other common diseases, genetic variants underlying alcoholism have been illusive, possibly due to the small effect from each individual susceptible variant, gene × environment and gene × gene interactions and complications in phenotype definition. We conducted association tests, the family-based association tests (FBAT) and the backward haplotype transmission association (BHTA), on the Collaborative Study of the Genetics of Alcoholism (COGA) data… CONTINUE READING

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