Whole-genome analysis of human astrocytic tumors by comparative genomic hybridization

@article{Maruno2000WholegenomeAO,
  title={Whole-genome analysis of human astrocytic tumors by comparative genomic hybridization},
  author={Motohiko Maruno and Hirotomo Ninomiya and A. K. M. Ghulam Muhammad and Masayuki Hirata and Amami Kato and Toshiki Yoshimine},
  journal={Brain Tumor Pathology},
  year={2000},
  volume={17},
  pages={21-27}
}
Frozen sections of 35 astrocytic tumors of various histologic malignancies were analyzed by comparative genomic hybridization in an attempt to characterize the profile of genetic aberrations. Over 94% of the samples revealed DNA copy number aberrations, which increased with higher histological malignancy grades, and also involvement of more than one… CONTINUE READING