Whole-exome sequencing to identify somatic mutations in peritoneal metastatic gastric adenocarcinoma: A preliminary study

@article{Liu2016WholeexomeST,
  title={Whole-exome sequencing to identify somatic mutations in peritoneal metastatic gastric adenocarcinoma: A preliminary study},
  author={Hao Liu and Fengping Li and Yu Zhu and Tingting Li and Haipeng Huang and Tian Lin and Yanfeng Hu and Xiaolong Qi and Jiang Yu and Guoxin Li},
  journal={Oncotarget},
  year={2016},
  volume={7},
  pages={43894 - 43906}
}
Peritoneal metastasis occurs in more than half of patients with unresectable or recurrent gastric cancer and is associated with the worst prognosis. The associated genomic events and pathogenesis remain ambiguous. The aim of the present study was to characterize the mutation spectrum of gastric cancer with peritoneal metastasis and provide a basis for the identification of new biomarkers and treatment targets. Matched pairs of normal gastric mucosa and peritoneal tissue and matched pairs of… 
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