Whole-cell current noise produced by excitatory and inhibitory amino acids in large cerebellar neurones of the rat.

@article{CullCandy1989WholecellCN,
  title={Whole-cell current noise produced by excitatory and inhibitory amino acids in large cerebellar neurones of the rat.},
  author={Stuart G Cull-Candy and Maria M. Usowicz},
  journal={The Journal of physiology},
  year={1989},
  volume={415},
  pages={533-53}
}
1. Membrane noise and current changes produced by glutamate and related excitatory amino acids have been examined in cultured large cerebellar neurones (including Purkinje cells), with whole-cell patch-clamp methods. The sensitivity of these neurones to the inhibitory amino acids gamma-aminobutyric acid (GABA) and glycine has also been studied. 2. The neurones formed inhibitory synapses in culture, and displayed spontaneous synaptic currents. Reducing the pipette Cl- concentration (i.e… CONTINUE READING