Whole-cell chloride currents in rat astrocytes accompany changes in cell morphology.

@article{Lascola1996WholecellCC,
  title={Whole-cell chloride currents in rat astrocytes accompany changes in cell morphology.},
  author={Christopher D. Lascola and Richard P. Kraig},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1996},
  volume={16 8},
  pages={
          2532-45
        }
}
Astrocytes can change shape dramatically in response to increased physiological and pathological demands, yet the functional consequences of morphological change are unknown. We report the expression of Cl- currents after manipulations that alter astrocyte morphology. Whole-cell Cl- currents were elicited after (1) rounding up cells by brief exposure to trypsin; (2) converting cells from a flat polygonal to a process-bearing (stellate) morphology by exposure to serum-free Ringer's solution; and… CONTINUE READING

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