Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial

@inproceedings{Fogarty2011WholeBR,
  title={Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial},
  author={Gerald B Fogarty and Rachael L Morton and Janette L Vardy and Anna K Nowak and Catherine Mandel and Peta Forder and Angela M. Hong and George Hruby and Bryan H. Burmeister and Brindha Shivalingam and Haryana M Dhillon and John F Thompson},
  booktitle={BMC Cancer},
  year={2011}
}
Cerebral metastases are a common cause of death in patients with melanoma. Systemic drug treatment of these metastases is rarely effective, and where possible surgical resection and/or stereotactic radiosurgery (SRS) are the preferred treatment options. Treatment with adjuvant whole brain radiotherapy (WBRT) following neurosurgery and/or SRS is controversial. Proponents of WBRT report prolongation of intracranial control with reduced neurological events and better palliation. Opponents state… CONTINUE READING
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Cognitive function and progression in patients with brain metastases treated with whole-brain radiation and motexafin gadolinium: results of a randomized phase III trial

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