Whole brain neuronal abnormalities in focal quantified with proton MR spectroscopy.

@article{Kirov2018WholeBN,
  title={Whole brain neuronal abnormalities in focal quantified with proton MR spectroscopy.},
  author={Ivan I. Kirov and Ruben I. Kuzniecky and Hoby P. Hetherington and Brian J. Soher and Matthew S. Davitz and James S. Babb and Heath R. Pardoe and J. W. Pan and Oded Gonen},
  journal={Epilepsy research},
  year={2018},
  volume={139},
  pages={85-91}
}
OBJECTIVE To test the hypothesis that localization-related epilepsy is associated with widespread neuronal dysfunction beyond the ictal focus, reflected by a decrease in patients' global concentration of their proton MR spectroscopy (1H-MRS) observed marker, N-acetyl-aspartate (NAA). METHODS Thirteen patients with localization-related epilepsy (7 men, 6… CONTINUE READING