Whole-brain calcium imaging with cellular resolution in freely behaving Caenorhabditis elegans

@article{Nguyen2015WholebrainCI,
  title={Whole-brain calcium imaging with cellular resolution in freely behaving Caenorhabditis elegans},
  author={J. Nguyen and Frederick B. Shipley and Ashley N. Linder and George S. Plummer and Mochi Liu and S. Setru and J. Shaevitz and Andrew M. Leifer},
  journal={Proceedings of the National Academy of Sciences},
  year={2015},
  volume={113},
  pages={E1074 - E1081}
}
  • J. Nguyen, Frederick B. Shipley, +5 authors Andrew M. Leifer
  • Published 2015
  • Biology, Physics, Chemistry, Computer Science, Medicine
  • Proceedings of the National Academy of Sciences
  • Significance Large-scale neural recordings in freely moving animals are important for understanding how patterns of activity across a population of neurons generates animal behavior. Previously, recordings have been limited to either small brain regions or to immobilized or anesthetized animals exhibiting limited behavior. This work records from neurons with cellular resolution throughout the entire brain of the nematode Caenorhabditis elegans during free locomotion. Neurons are found whose… CONTINUE READING
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