Whole body pharmacokinetic models.

@article{Nestorov2003WholeBP,
  title={Whole body pharmacokinetic models.},
  author={Ivan Nestorov},
  journal={Clinical pharmacokinetics},
  year={2003},
  volume={42 10},
  pages={883-908}
}
The aim of the current review is to summarise the present status of physiologically based pharmacokinetic (PBPK) modelling and its applications in drug research, and thus serve as a reference point to people interested in the methodology. The review is structured into three major sections. The first discusses the existing methodologies and techniques of PBPK model development. The second describes some of the most interesting PBPK model implementations published. The final section is devoted to… CONTINUE READING

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