Whole-body distribution of 14C-labeled silica nanoparticles and submicron particles after intravenous injection into Mice

@article{Sakai2012WholebodyDO,
  title={Whole-body distribution of 14C-labeled silica nanoparticles and submicron particles after intravenous injection into Mice},
  author={Nobumitsu Sakai and Masato Takakura and Harutoshi Imamura and Miki Sugimoto and Yasuto Matsui and Hirokazu Miyoshi and Aki Nakayama and Minoru Yoneda},
  journal={Journal of Nanoparticle Research},
  year={2012},
  volume={14},
  pages={1-11}
}
We analyzed the whole-body distribution of 14C–ADP-labeled silica nanoparticles (14C–ADP–SiO2 nanoparticles) and submicron particles (14C–ADP–SiO2 submicron particles) after intravenous injection into ICR mice. The 14C–ADP–SiO2 nanoparticles and submicron particles were synthesized before the injection and the particle size was 19.6 and 130 nm, respectively. Similarly, the shape was spherical and the crystallinity was amorphous. After the synthesis, we injected mice with the 14C–ADP–SiO2… CONTINUE READING

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