Whole blood aggregation and coagulation in db/db and ob/ob mouse models of type 2 diabetes.

@article{Henry2008WholeBA,
  title={Whole blood aggregation and coagulation in db/db and ob/ob mouse models of type 2 diabetes.},
  author={Melissa L. Henry and Lisa B. Davidson and Jonathan E Wilson and Brenda K McKenna and Sheree A Scott and P 4 Mariojouls C 9 Muir J F 1 Prothero McDonagh and Leslie S Ritter},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2008},
  volume={19 2},
  pages={124-34}
}
Type 2 diabetes in humans is associated with a significant hypercoagulable state; however, the effects of this on stroke and cardiovascular disease are not completely understood. The genetic mutations in db/db and ob/ob mice produce metabolic abnormalities similar to type 2 diabetes, but little is known about their platelet or coagulation properties. The objective of this study was therefore to examine platelet function and coagulation in db/db and ob/ob mice to determine the degree of… CONTINUE READING

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Blood coagulation and metabolic profiles in middle-aged male and female ob/ob mice.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis • 2015

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