Whole-blood 3-hydroxyisovalerylcarnitine as a risk factor for orofacial clefts.

@article{Budner2013Wholeblood3A,
  title={Whole-blood 3-hydroxyisovalerylcarnitine as a risk factor for orofacial clefts.},
  author={Margareta Budner and Zbigniew Surowiec and Piotr Stanislaw Fudalej and Kamil Konrad Hozyasz},
  journal={Archives of oral biology},
  year={2013},
  volume={58 5},
  pages={459-61}
}
BACKGROUND/PURPOSE In mice, biotin deficiency is one of the most potent clefting factors. Increased 3-hydroxyisovalerylcarnitine (C5OH) is regarded as a biomarker of biotin deficiency. This retrospective study was undertaken to determine whether increased C5OH in newborns is associated with orofacial clefts. MATERIALS AND METHODS Seventy newborns with non… CONTINUE READING