Whole Transcriptome Profiling Identifies CD93 and Other Plasma Cell Survival Factor Genes Associated with Measles-Specific Antibody Response after Vaccination

@inproceedings{Haralambieva2016WholeTP,
  title={Whole Transcriptome Profiling Identifies CD93 and Other Plasma Cell Survival Factor Genes Associated with Measles-Specific Antibody Response after Vaccination},
  author={Iana H. Haralambieva and Michael T. Zimmermann and Inna G. Ovsyannikova and Diane E. Grill and Ann L. Oberg and Richard B. Kennedy and Gregory A. Poland},
  booktitle={PloS one},
  year={2016}
}
BACKGROUND There are insufficient system-wide transcriptomic (or other) data that help explain the observed inter-individual variability in antibody titers after measles vaccination in otherwise healthy individuals. METHODS We performed a transcriptome(mRNA-Seq)-profiling study after in vitro viral stimulation of PBMCs from 30 measles vaccine recipients, selected from a cohort of 764 schoolchildren, based on the highest and lowest antibody titers. We used regression and network biology… CONTINUE READING
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