Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes

@article{Aparcio2002WholeGenomeSA,
  title={Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes},
  author={S. Apar{\'i}cio and J. Chapman and E. Stupka and N. Putnam and Jer-Ming Chia and Paramvir S. Dehal and A. Christoffels and Sam Rash and Shawn S Hoon and A. Smit and M. Gelpke and J. Roach and T. Oh and Isaac Y. Ho and Marie Wong and C. Detter and F. Verhoef and P. Predki and Alice Tay and S. Lucas and P. Richardson and Sarah F. Smith and M. Clark and Y. Edwards and N. Doggett and A. Zharkikh and S. Tavtigian and D. Pruss and M. Barnstead and C. Evans and H. Baden and Justin Powell and Gustavo Glusman and L. Rowen and L. Hood and Y. H. Tan and G. Elgar and T. Hawkins and B. Venkatesh and D. Rokhsar and S. Brenner},
  journal={Science},
  year={2002},
  volume={297},
  pages={1301 - 1310}
}
The compact genome of Fugu rubripes has been sequenced to over 95% coverage, and more than 80% of the assembly is in multigene-sized scaffolds. In this 365-megabase vertebrate genome, repetitive DNA accounts for less than one-sixth of the sequence, and gene loci occupy about one-third of the genome. As with the human genome, gene loci are not evenly distributed, but are clustered into sparse and dense regions. Some “giant” genes were observed that had average coding sequence sizes but were… Expand
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