Whole-Genome Analysis of Temporal Gene Expression during Foregut Development

  title={Whole-Genome Analysis of Temporal Gene Expression during Foregut Development},
  author={Jeb Gaudet and Srikanth Muttumu and Michael T. Horner and Susan E Mango},
  journal={PLoS Biology},
  pages={561 - 574}
We have investigated the cis-regulatory network that mediates temporal gene expression during organogenesis. Previous studies demonstrated that the organ selector gene pha-4/FoxA is critical to establish the onset of transcription of Caenorhabditis elegans foregut (pharynx) genes. Here, we discover additional cis-regulatory elements that function in combination with PHA-4. We use a computational approach to identify candidate cis-regulatory sites for genes activated either early or late during… CONTINUE READING
54 Citations
89 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 54 extracted citations


Publications referenced by this paper.
Showing 1-10 of 89 references

Environmentally-induced foregut remodelling is mediated by convergent downstream regulation by PHA-4/FoxA and the DAF-12 nuclear hormone receptor

  • W Ao, J Gaudet, SE Mango
  • Science
  • 2004
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…