Who is healthy? Aspects to consider when including healthy volunteers in QST--based studies-a consensus statement by the EUROPAIN and NEUROPAIN consortia.

@article{Gierthmuehlen2015WhoIH,
  title={Who is healthy? Aspects to consider when including healthy volunteers in QST--based studies-a consensus statement by the EUROPAIN and NEUROPAIN consortia.},
  author={Janne Gierthmuehlen and Elena K. Enax-Krumova and Nadine Attal and Didier Bouhassira and Giorgio Cruccu and N. B. Finnerup and Maija L Haanp{\"a}{\"a} and Per O Hansson and Troels Staehelin Jensen and Rainer Freynhagen and Jeffrey D. Kennedy and Tina Mainka and Andrew C. Rice and M{\"a}rta Segerdahl and S\oren Hein Sindrup and Jordi Serra and Thomas R. T{\"o}lle and Rolf-Detlef Treede and Ralf Baron and Christoph E Maier},
  journal={Pain},
  year={2015},
  volume={156 11},
  pages={2203-11}
}
Clinical and human experimental pain studies often include so-called "healthy" controls in investigations of sensory abnormalities, using quantitative sensory testing (QST) as an outcome measure. However, the criteria for what is considered "healthy" vary among the different studies and between study centers and investigators, partly explaining the high variability of the results. Therefore, several aspects should be considered during inclusion of healthy volunteers in QST-based trials to have… CONTINUE READING
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