Who gets recruited in mild traumatic brain injury research?

@article{Luoto2013WhoGR,
  title={Who gets recruited in mild traumatic brain injury research?},
  author={Teemu Miikka Luoto and Olli Tenovuo and Anneli Kataja and Antti Brander and Juha {\"O}hman and Grant L. Iverson},
  journal={Journal of neurotrauma},
  year={2013},
  volume={30 1},
  pages={
          11-6
        }
}
Selection bias, common in traumatic brain injury research, limits the clinical usefulness and generalizability of study findings. The purpose of this study was to examine the effect of different inclusion and exclusion criteria on patient enrollment, and the implications for generalizability, in a mild traumatic brain injury (MTBI) study. The study was conducted at the emergency department (ED) of Tampere University Hospital. Our aim was to study outcome from MTBI in patients who do not have… 
Clinical Assessment of Acute Mild Traumatic Brain Injury
TLDR
This study examined the effect of different inclusion and exclusion criteria on patient enrollment, and the implications for generalizability, in a mild traumatic brain injury (MTBI) study, conducted at the emergency department of Tampere University Hospital.
The effect of sampling bias on generalizability in intervention trials after brain injury
TLDR
Strict inclusion and exclusion criteria render the study population less representative and, thus, reduces generalizability, and the use of broad inclusion criteria and common data elements and the need to report data from the total patient population is advocated.
Who Gets Head Trauma or Recruited in Mild Traumatic Brain Injury Research?
TLDR
Pre-injury health characteristics of all consecutive patients who underwent head computed tomography due to acute head trauma in the emergency department of Tampere University Hospital, Finland, between August 2010 and July 2012 were examined.
The epidemiology of mild traumatic brain injury: the Trondheim MTBI follow-up study
TLDR
Two thirds of all patients with MTBI in the 16–60 age group were treated without hospital admission, patients were often young, and half of the patients presented during the weekend, which needs to be addressed when considering strategies for prevention.
Sport concussion assessment tool 2 in a civilian trauma sample with mild traumatic brain injury.
TLDR
The SCAT2 appears useful for detecting acute mTBI-related symptoms and cognitive impairment, refining prognosis, and monitoring recovery, and was superior to the MACE.
Clinical correlates of retrograde amnesia in mild traumatic brain injury
TLDR
The presence and duration of RA were not significantly associated with PCS diagnosis or time to RTW or clinical outcomes at 2 weeks, 1 month and 6 months post-injury.
Missing a follow-up after mild traumatic brain injury—Does it matter?
TLDR
Not attending the follow-up has a favourable outcome after MBTI, indicating that patients with a mild traumatic brain injury have a reduced need for medical and rehabilitation support for their brain injury.
Injury profiles, demography and representativeness of patients with TBI attending a regional emergency department
TLDR
It is supported that falls are the most common injury mechanism in the Western countries and uncertainty about the diagnosis of TBI, lack of representativeness without continuous recruitment and poor information transfer about the ED attendees are major challenges for prospective TBI studies.
Resilience and Other Possible Outcomes After Mild Traumatic Brain Injury: a Systematic Review
TLDR
Three of these studies showed that greater trait resilience was associated with better mild TBI outcomes (fewer symptoms) and future research of the adult Mild TBI response that predicts a resilient outcome is encouraged.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 24 REFERENCES
Outcome after mild traumatic brain injury: an examination of recruitment bias
TLDR
Premorbid factors did not predict whether patients comply with, or refuse study participation, however, the participants group was biased toward those with more significant injuries, which translated into higher rates of healthcare utilisation after injury.
Importance of screening logs in clinical trials for severe traumatic brain injury.
TLDR
The experience shows the feasibility of collecting screening logs and illustrates how the potential for selection bias may creep into well-designed randomized clinical trials as a result of factors outside the control of investigators.
Systematic bias in traumatic brain injury outcome studies because of loss to follow-up.
TLDR
TBI follow-up studies may experience selective attrition of subjects who are socioeconomically disadvantaged, have a history of substance abuse, and have violent injury etiologies, which is mitigated for those with more severe motor deficits.
Acute Assessment of Brain Injuries in Ground-Level Falls
TLDR
Older age and long-term alcohol abuse increase the likelihood of acute intracranial CT abnormalities, and the pattern of intrac Cranial traumatic CT findings does not differ from other causes of TBI.
Protocol for a systematic review of prognosis after mild traumatic brain injury: an update of the WHO Collaborating Centre Task Force findings
TLDR
The results of this study form the basis for a better understanding of recovery after MTBI, and will allow development of prediction tools and recommendation of interventions, as well as informing health policy and setting a future research agenda.
Methodological issues and research recommendations for mild traumatic brain injury: the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury.
The WHO Collaborating Centre for Neurotrauma Task Force on Mild Traumatic Brain Injury performed a comprehensive search and critical review of the literature published between 1980 and 2002 to
Factors associated with mortality and brain injury after falls from the standing position.
TLDR
FFS is a potentially morbid mechanism of injury in those who are using warfarin, those with Glasgow Coma Scale score <or=12, and those who is not inebriated.
Position statement: definition of traumatic brain injury.
Permanent post-concussion symptoms after mild head injury
TLDR
Age, pre-/post-morbid concomitant factors, neuropsychological deficits and emotional status are key variables in understanding the phenomenon of permanent PCS.
...
1
2
3
...