Who Ate Whom? Adaptive Helicobacter Genomic Changes That Accompanied a Host Jump from Early Humans to Large Felines

@article{Eppinger2006WhoAW,
  title={Who Ate Whom? Adaptive Helicobacter Genomic Changes That Accompanied a Host Jump from Early Humans to Large Felines},
  author={Mark Eppinger and Claudia Baar and Bodo Linz and G{\"u}nter Raddatz and Christa Lanz and Heike R Gudat Keller and Giovanna Morelli and Helga Gressmann and Mark Achtman and Stephan C. Schuster},
  journal={PLoS Genetics},
  year={2006},
  volume={2},
  pages={1175 - 1186}
}
Helicobacter pylori infection of humans is so old that its population genetic structure reflects that of ancient human migrations. A closely related species, Helicobacter acinonychis, is specific for large felines, including cheetahs, lions, and tigers, whereas hosts more closely related to humans harbor more distantly related Helicobacter species. This observation suggests a jump between host species. But who ate whom and when did it happen? In order to resolve this question, we determined the… CONTINUE READING
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