Who, What, Where, When (and Maybe Even Why)? How the Experience of Sexual Reward Connects Sexual Desire, Preference, and Performance

  title={Who, What, Where, When (and Maybe Even Why)? How the Experience of Sexual Reward Connects Sexual Desire, Preference, and Performance},
  author={James G. Pfaus and Tod E. Kippin and Genaro A Coria-Avila and H{\'e}l{\`e}ne Gelez and Veronica M. Afonso and Nafissa Ismail and Mayte Parada},
  journal={Archives of Sexual Behavior},
Although sexual behavior is controlled by hormonal and neurochemical actions in the brain, sexual experience induces a degree of plasticity that allows animals to form instrumental and Pavlovian associations that predict sexual outcomes, thereby directing the strength of sexual responding. This review describes how experience with sexual reward strengthens the development of sexual behavior and induces sexually-conditioned place and partner preferences in rats. In both male and female rats… 

Behavioral, Neural, and Molecular Mechanisms of Conditioned Mate Preference: The Role of Opioids and First Experiences of Sexual Reward

From a comprehensive review of the available data, it is concluded that opioid transmission at μ opioid receptors forms the basis of sexual pleasure and reward, which then sensitizes dopamine, oxytocin, and vasopressin systems responsible for attention, arousal, and bonding, leading to cortical activation that creates awareness of attraction and desire.

Effect of CS preexposure on the conditioned ejaculatory preference of the male rat: behavioral analyses and neural correlates

Exposure to the scent before perfusion for inmunohistochemistry revealed different patterns of brain activation in brain areas previously associated with the development of partner preference, like the medial preoptic area, ventral tegmental area, nucleus accumbens, basolateral amygdala, depending on group membership.

Opioids and sexual reward

  • R. Paredes
  • Biology, Psychology
    Pharmacology Biochemistry and Behavior
  • 2014

The Role of Brain Opioid Transmission in the Conditioned Ejaculatory Preference of the Male Rat

The results show that opioids are an important substrate of the sexual reward state, and that this state feeds forward to form a conditioned ejaculatory preference (CEP), in which male rats ejaculate preferentially with females bearing or wearing the cue associated with sexual reward.

The role of orgasm in the development and shaping of partner preferences

How UCS- and CS-detection centers must interact to facilitate memory consolidation and produce recognition and motivation during future social encounters is discussed.



What Can Animal Models Tell Us about Human Sexual Response?

Identification of common neurochemical and neuroanatomical substrates of sexual responding between animals and humans suggests that the evolution of sexual behavior has been highly conserved and indicates that animal models of human sexual response can be used successfully as preclinical tools.

What do female rats like about sex? Paced mating

Learning about sex: conditioning of partner preference: theoretical comment on Coria-Avila et Al. (2005).

  • M. Erskine
  • Psychology, Biology
    Behavioral neuroscience
  • 2005
The results suggest that establishment of a partner preference depends on rewarding characteristics of the vaginocervical stimulation the female receives during an initial mating and that selection of a sexual partner can be determined by olfactory stimuli associated with that stimulation.

Sexual Behaviour and Sexual Motivation in the Female Rat

In the experiment reported here, the choice of an individual female for a potent (copulating) as against an impotent male was examined, using a T-maze.

Sexual motivation: A neural and behavioural analysis of the mechanisms underlying appetitive and copulatory responses of male rats

  • B. Everitt
  • Psychology, Biology
    Neuroscience & Biobehavioral Reviews
  • 1990

Sexual Behavior Induction of c-Fos in the Nucleus Accumbens and Amphetamine-Stimulated Locomotor Activity Are Sensitized by Previous Sexual Experience in Female Syrian Hamsters

The data indicate that female sexual behavior can activate neurons in the nucleus accumbens and that sexual experience can cross-sensitize neuronal responses to amphetamine, and provide additional evidence for functional differences between the shell and core of the nucleus AccumbENS and across its anteroposterior axis.

Considering the Role of Conditioning in Sexual Orientation

The investigation of contributions and limitations of conditioning processes to explaining how cues acquire erotic value is renewed and some integration between the sexual conditioning literature and research on sexual orientation or more generally sexual partner preference is attempted.

Female rats develop conditioned place preferences for sex at their preferred interval

The roots of sexual arousal and sexual orientation.

  • Y. Salu
  • Psychology, Biology
    Medical hypotheses
  • 2011