Whither goest the RGS proteins?

  title={Whither goest the RGS proteins?},
  author={David P. Siderovski and Bentley Strockbine and C I Behe},
  journal={Critical reviews in biochemistry and molecular biology},
  volume={34 4},
Studies of the desensitization of G protein-coupled signal transduction have led to the discovery of a family of guanosine triphosphatase-activating proteins (GAPs) for heterotrimeric G protein alpha subunits - the "regulator of G protein signaling" or RGS proteins. In considering both documented and potential functions of several RGS protein family members with demonstrable multidomain compositions (p115RhoGEF, PDZRhoGEF, Axin, Axil/Conductin, D-AKAP2, the G protein-coupled receptor kinases… CONTINUE READING

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