White matter lesions as a predictor of depression in the elderly: the 3C-Dijon study.

@article{Godin2008WhiteML,
  title={White matter lesions as a predictor of depression in the elderly: the 3C-Dijon study.},
  author={Ophelia Godin and Carole Dufouil and Pauline Maillard and Nicolas Delcroix and Bernard Mazoyer and Fabrice Crivello and Annick Alp{\'e}rovitch and Christophe Tzourio},
  journal={Biological psychiatry},
  year={2008},
  volume={63 7},
  pages={663-9}
}
BACKGROUND There is increasing evidence for a link between cerebrovascular disease and depression in the elderly but the mechanisms are still unknown. This study examines the longitudinal relationship between depression and white matter lesions (WML) in a sample of elderly aged 65 years and older. METHODS Three City (3C)-Dijon is a 4-year follow-up population-based prospective study of 1658 subjects. At baseline, lifetime major depressive episode diagnosis was established using the Mini… CONTINUE READING
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