White matter lesions and temporal lobe atrophy related to incidence of both dementia and major depression in 70-year-olds followed over 10 years.

@article{Gudmundsson2015WhiteML,
  title={White matter lesions and temporal lobe atrophy related to incidence of both dementia and major depression in 70-year-olds followed over 10 years.},
  author={Pia Gudmundsson and Pernille J Olesen and Michela Simoni and Leonardo Pantoni and Svante {\"O}stling and Silke Kern and Xinxin Guo and Ingmar Skoog},
  journal={European journal of neurology},
  year={2015},
  volume={22 5},
  pages={781-8, e49-50}
}
BACKGROUND AND PURPOSE A number of studies have suggested associations between dementia and depression in older adults. One reason could be that these disorders share structural correlates, such as white matter lesions (WMLs) and cortical atrophy. No study has examined whether these lesions precede both dementia and depression independently of each other in the general population. METHODS Whether WMLs and cortical atrophy on computed tomography predict dementia and depression was investigated… CONTINUE READING
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