White matter integrity correlates of implicit sequence learning in healthy aging.

@article{Bennett2011WhiteMI,
  title={White matter integrity correlates of implicit sequence learning in healthy aging.},
  author={Ilana J. Bennett and David J. Madden and Chandan J. Vaidya and James H. Howard and Darlene V. Howard},
  journal={Neurobiology of aging},
  year={2011},
  volume={32 12},
  pages={2317.e1-12}
}
Previous research has identified subcortical (caudate, putamen, hippocampus) and cortical (dorsolateral prefrontal cortex, DLPFC; frontal motor areas) regions involved in implicit sequence learning, with mixed findings for whether these neural substrates differ with aging. The present study used diffusion tensor imaging (DTI) tractography to reconstruct white matter connections between the known gray matter substrates, and integrity of these tracts was related to learning in the alternating… CONTINUE READING
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