White matter impairment in the basal ganglia-thalamocortical circuit of drug-naïve childhood absence epilepsy.

@article{Yang2012WhiteMI,
  title={White matter impairment in the basal ganglia-thalamocortical circuit of drug-na{\"i}ve childhood absence epilepsy.},
  author={Tianhua Yang and Zhiwei Guo and Cheng Luo and Qifu Li and Bo Yan and Liu Ling and Qiyong Gong and D. Yao and Dong Zhou},
  journal={Epilepsy research},
  year={2012},
  volume={99 3},
  pages={267-73}
}
PURPOSE It is unknown whether white matter abnormalities exist in childhood absence epilepsy (CAE), a syndrome of idiopathic epilepsy (IGE). Diffusion tensor imaging (DTI) can noninvasively quantify white matter integrity. This study used DTI to investigate abnormal changes in white matter of untreated CAE patients. METHODS Subjects included nine patients with untreated CAE and nine age-and sex-matched healthy controls. Diffusion tensor imaging parameters were voxel based and statistically… CONTINUE READING

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