White matter hypoperfusion and damage in dementia: post-mortem assessment.

@article{Love2015WhiteMH,
  title={White matter hypoperfusion and damage in dementia: post-mortem assessment.},
  author={Seth Love and J S Miners},
  journal={Brain pathology},
  year={2015},
  volume={25 1},
  pages={99-107}
}
Neuroimaging has revealed a range of white matter abnormalities that are common in dementia, some that predict cognitive decline. The abnormalities may result from structural diseases of the cerebral vasculature, such as arteriolosclerosis and amyloid angiopathy, but can also be caused by nonstructural vascular abnormalities (eg, of vascular contractility or permeability), neurovascular instability or extracranial cardiac or vascular disease. Conventional histopathological assessment of the… CONTINUE READING

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