White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age

@inproceedings{Boyle2016WhiteMH,
  title={White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age},
  author={Patricia A. Boyle and Lei Yu and Debra A. Fleischman and S E Leurgans and Jingyun Yang and Robert Smith Wilson and Julie A Schneider and Zoe Arvanitakis and Konstantinos Arfanakis and David A. Bennett},
  booktitle={Annals of clinical and translational neurology},
  year={2016}
}
OBJECTIVE Examine the association of white matter hyperintensities (WMH) with risk of incident mild cognitive impairment (MCI) and rate of decline in multiple cognitive systems in community-based older persons. METHODS Participants (n = 354) were older persons initially free of cognitive impairment from two ongoing longitudinal epidemiologic studies of aging. All underwent brain magnetic resonance imaging (MRI) for quantification of WMH and gray matter volumes and detailed annual clinical… CONTINUE READING
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