White matter edema at the early stage of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

@article{Guio2015WhiteME,
  title={White matter edema at the early stage of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy.},
  author={F De Guio and Jean-Francois Mangin and Marco Duering and Stefan Ropele and Hugues Chabriat and Eric Jouvent},
  journal={Stroke},
  year={2015},
  volume={46 1},
  pages={258-61}
}
BACKGROUND AND PURPOSE Recently, in a mouse model of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy, a monogenic cerebral small vessel disease, intramyelinic edema was detected in the white matter (WM) early during the course of the disease. We hypothesized that if this mechanism holds true in patients, it would translate in larger WM volume. We aimed to measure WM volume in patients with cerebral autosomal-dominant arteriopathy with subcortical… CONTINUE READING