White matter disease independently predicts progression from mild cognitive impairment to Alzheimer's disease in a clinic cohort.

Abstract

BACKGROUND The contribution of vascular pathology to the rate of progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) remains unclear. OBJECTIVE To ascertain the relative roles of cerebral white matter disease and medial temporal atrophy (MTA) in predicting progression from MCI to AD. METHODS MCI patients with baseline MRI and… (More)
DOI: 10.1159/000330019

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