White matter abnormalities in schizophrenia patients with tardive dyskinesia: a diffusion tensor image study.

@article{Bai2009WhiteMA,
  title={White matter abnormalities in schizophrenia patients with tardive dyskinesia: a diffusion tensor image study.},
  author={Yamei Bai and Kun-Hsien Chou and Ching-Po Lin and I-Yun Chen and Cheng-Ta Li and Kai Chun Yang and Yuan-Hwa Chou and Tung-Ping Su},
  journal={Schizophrenia research},
  year={2009},
  volume={109 1-3},
  pages={167-81}
}
OBJECTIVE Tardive dyskinesia (TD) is a severe side effect of antipsychotics. While increasing evidence suggests that damaged brain microcircuitry of white matter (WM) is responsible for the clinical symptoms in schizophrenia, no reports of WM abnormality associated with TD were noted. METHOD Brain white matter abnormalities were investigated among 20 schizophrenia patients with TD (Schizophrenia with TD group), 20 age-, gender-, and handedness-matched schizophrenic patients without TD… CONTINUE READING