White matter abnormalities in children and adolescents with obsessive-compulsive disorder: a diffusion tensor imaging study.

@article{Jayarajan2012WhiteMA,
  title={White matter abnormalities in children and adolescents with obsessive-compulsive disorder: a diffusion tensor imaging study.},
  author={Rajan Nishanth Jayarajan and Ganesan Venkatasubramanian and Biju Viswanath and Y. C. Janardhan Reddy and Shoba Srinath and Mandapatti Krishnamurthy Vasudev and Channapatna R. Chandrashekar},
  journal={Depression and anxiety},
  year={2012},
  volume={29 9},
  pages={780-8}
}
BACKGROUND There is paucity of data on white matter (WM) abnormalities in juvenile obsessive-compulsive disorder (OCD). This study aimed to identify WM microstructure changes in juvenile OCD. METHODS Fifteen children and adolescents with OCD and 15 matched healthy controls underwent diffusion tensor imaging using a 3 Tesla (Achieva, Best, The Netherlands) magnetic resonance imaging scanner. Voxelwise analyses were conducted on data processed through tract-based spatial statistics (TBSS… CONTINUE READING
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