White blood cell count, sex and age are major determinants of heterogeneity of platelet indices in an adult general population: results from the MOLI-SANI project.

@article{Santimone2011WhiteBC,
  title={White blood cell count, sex and age are major determinants of heterogeneity of platelet indices in an adult general population: results from the MOLI-SANI project.},
  author={Iolanda Santimone and Augusto F Di Castelnuovo and Amalia de Curtis and Maria Ang{\'e}lica do Santos Spinelli and Daniela Cugino and Francesco Gianfagna and Francesco Zito and Maria Benedetta Donati and C. Cerletti and Giovanni de Gaetano and Licia Iacoviello},
  journal={Haematologica},
  year={2011},
  volume={96 8},
  pages={1180-8}
}
BACKGROUND The understanding of non-genetic regulation of platelet indices--platelet count, plateletcrit, mean platelet volume, and platelet distribution width--is limited. The association of these platelet indices with a number of biochemical, environmental and clinical variables was studied in a large cohort of the general population. DESIGN AND METHODS Men and women (n=18,097, 52% women, 56±12 years) were randomly recruited from various villages in Molise (Italy) in the framework of the… CONTINUE READING

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