White and Gray Matter Abnormalities After Cranial Radiation in Children and Mice.

@article{Nieman2015WhiteAG,
  title={White and Gray Matter Abnormalities After Cranial Radiation in Children and Mice.},
  author={Brian J. Nieman and A Elizabeth de Guzman and Lisa M Gazdzinski and Jason P. Lerch and M. Mallar Chakravarty and Jon Pipitone and Douglas R. Strother and Chris Fryer and Eric Bouffet and Suzanne Laughlin and Normand Laperriere and Lily Riggs and Jovanka Skocic and Donald J Mabbott},
  journal={International journal of radiation oncology, biology, physics},
  year={2015},
  volume={93 4},
  pages={882-91}
}
PURPOSE Pediatric patients treated with cranial radiation are at high risk of developing lasting cognitive impairments. We sought to identify anatomical changes in both gray matter (GM) and white matter (WM) in radiation-treated patients and in mice, in which the effect of radiation can be isolated from other factors, the time course of anatomical change can be established, and the effect of treatment age can be more fully characterized. Anatomical results were compared between species… CONTINUE READING
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