Whipple's disease confined to the central nervous system

  title={Whipple's disease confined to the central nervous system},
  author={B{\'e}atrice De Coene and Claude Gilliard and P. Indeken and T. P. J. Duprez and Jean Paul Trigaux},
We report a 49-year-old woman with a leaft parietal lesion, shown on CT and MRI as an isolated ring-enhancing mass. The diagnosis of cerebral Whipple's disease was made by brain biopsy; there were no gastrointestinal symptoms nor periodic-acid Schiff-positive inclusions in the jejunal mucosa. This case illustrates atypical Whipple's disease, confined exclusively to the central nervous system.