Which time-to-peak threshold best identifies penumbral flow? A comparison of perfusion-weighted magnetic resonance imaging and positron emission tomography in acute ischemic stroke.

@article{Sobesky2004WhichTT,
  title={Which time-to-peak threshold best identifies penumbral flow? A comparison of perfusion-weighted magnetic resonance imaging and positron emission tomography in acute ischemic stroke.},
  author={Jan Sobesky and Olivier Zaro Weber and F-G Lehnhardt and Volker Hesselmann and Adelheit Stein Ulrich Thiel and Christian Dohmen and Adam Jacobs and Michael Neveling and W-D Heiss},
  journal={Stroke},
  year={2004},
  volume={35 12},
  pages={2843-7}
}
BACKGROUND AND PURPOSE In acute ischemic stroke, the hypoperfused but viable tissue is the main therapeutic target. In clinical routine, time-to-peak (TTP) maps are frequently used to estimate the hemodynamic compromise and to calculate the mismatch volume. We evaluated the accuracy of TTP maps to identify penumbral flow by comparison with positron emission tomography (PET). METHODS Magnetic resonance imaging (MRI) and PET were performed in 11 patients with acute ischemic stroke (median 8… CONTINUE READING

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: present status

  • PA Barber, MW Parsons, +4 authors SM Davis
  • 2003

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