Which therapy for which patient?

@article{Pierangeli2006WhichTF,
  title={Which therapy for which patient?},
  author={Giulia Pierangeli and Sabina Cevoli and Elisa Sancisi and Daniela Grimaldi and Stefano Zanigni and Pasquale Montagna and Pietro Cortelli},
  journal={Neurological Sciences},
  year={2006},
  volume={27},
  pages={s153-s158}
}
Prophylactic treatment is mainly intended to reduce the frequency of migraine attacks, enhance response to acute medications, improve patient function and reduce disability. Sufficient evidence and consensus exist to recommend propranolol, timolol, amitriptyline, pizotifen, divalproex, sodium valproate and topiramate as first line agents for migraine prevention. These drugs can halve the frequency of attacks in 50% of patients. The anticipated benefit must be weighed against the adverse effects… 

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