Which patients with antiphospholipid antibody should be treated and how?

@article{Lockshin1993WhichPW,
  title={Which patients with antiphospholipid antibody should be treated and how?},
  author={Michael D. Lockshin},
  journal={Rheumatic diseases clinics of North America},
  year={1993},
  volume={19 1},
  pages={235-47}
}
The tests for antiphospholipid antibody are relatively crude but usable. Asymptomatic persons with incidentally discovered antiphospholipid antibody do not need treatment. Those with symptoms are best treated with anticoagulation, but data specifically supporting aspirin, heparin, or warfarin or combinations thereof remain to be generated. High-dose corticosteroid therapy has at best equivocal efficacy and much toxicity and should be used only for lupus activity and not for phenomena of the… CONTINUE READING

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