Which oral antidiabetic drug to combine with metformin to minimize the risk of hypoglycemia when initiating basal insulin?: A randomized controlled trial of a DPP4 inhibitor versus insulin secretagogues.

Abstract

We conducted a pilot study to evaluate two therapeutic strategies at the time of insulin initiation in type 2 diabetic patients insufficiently controlled with metformin+insulin-secretagogues (IS, sulfonylureas or glinides). Patients were randomized to remain under the same dual therapy or to receive metformin+DPP4 inhibitors while starting insulin. Similar… (More)
DOI: 10.1016/j.diabres.2016.04.008

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Cite this paper

@article{Gautier2016WhichOA, title={Which oral antidiabetic drug to combine with metformin to minimize the risk of hypoglycemia when initiating basal insulin?: A randomized controlled trial of a DPP4 inhibitor versus insulin secretagogues.}, author={Jean - François Gautier and P Monguillon and Odile V{\'e}rier-Mine and Paul E Valensi and B{\'e}atrice Fiquet and Sylvie Dejager and Bernard H Charbonnel}, journal={Diabetes research and clinical practice}, year={2016}, volume={116}, pages={26-8} }