Which model for propofol TCI in children.

@article{Constant2010WhichMF,
  title={Which model for propofol TCI in children.},
  author={I. Constant and Agn{\`e}s Rigouzzo},
  journal={Paediatric anaesthesia},
  year={2010},
  volume={20 3},
  pages={233-9}
}
For several years, total intravenous anesthesia (TIVA) has demonstrated many advantages that allow consideration of propofol anesthesia as an interesting alternative in pediatric anesthesia. TIVA in children requires calculation and validation of pharmacokinetic (PK) models specifically adapted to the pediatric population. Several PK models based on a 3-compartment approach have been proposed in children: all these models, which integrate only weight as covariable, show increased distribution… CONTINUE READING
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Development of a WHO growth reference for school-aged children and adolescents

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