Which hormone tests for the diagnosis of polycystic ovary syndrome?

@article{Robinson1992WhichHT,
  title={Which hormone tests for the diagnosis of polycystic ovary syndrome?},
  author={Shannon Robinson and D. A. Rodin and Alyssa Deacon and Michael J. Wheeler and Richard N. Clayton},
  journal={BJOG: An International Journal of Obstetrics \& Gynaecology},
  year={1992},
  volume={99}
}
Objective To assess the frequency of abnormal values for hormone measurements commonly used in the biochemical diagnosis of polycystic ovary syndrome (PCOS). 
How common are polycystic ovaries in normal women and what is their significance for the fertility of the population?
TLDR
The prevalence of polycystic ovaries (PCO) and relate morphological appearance to fertility are determined and the relationship to fertility is related to morphology. Expand
Polycystic ovary syndrome. A diagnostic challenge.
  • V. Lewis
  • Medicine
  • Obstetrics and gynecology clinics of North America
  • 2001
Polycystic ovary syndrome remains a diagnostic challenge because there is no single defining test. The clinical presentation must dictate the extent of the work-up. The typical PCOS patient has aExpand
Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian women
To determine the prevalence of polycystic ovaries (PCO) in Asian women living in England who are of Indian subcontinent origin or ancestry and to investigate the relationship between the presence ofExpand
Insulin sensitivity and fertility
TLDR
Information is presented to demonstrate that prolonged anovulation decreases insulin sensitivity and, conversely, that improvement in insulin sensitivity normalizes ovarian function in PCOS. Expand
Polycystic ovary syndrome
TLDR
It is of interest to realize that polycystic ovary syndrome has moved from a histology diagnosis of ovarian tissue to a heterogeneous clinical syndrome, to a reproductive endocrine abnormality with elevated serum luteinizing hormone and androgen levels, and to a metabolic disease characterized by hyperinsulinemia and dyslipidemia. Expand
The Predictive Power of Endocrine Tests for the Diagnosis of Polycystic Ovaries in Women with Oligoamenorrhea
TLDR
The diagnostic characteristics of LH/FSH ratio and insulin for PCOS when compared by receiver-operator characteristic analysis were found to be equally effective and by combining these two variables a higher area under curve was obtained. Expand
Optimal use of hormone determinations in the biochemical diagnosis of the polycystic ovary syndrome.
TLDR
Simultaneous use of the levels of LH, FSH, and A in serum can be used effectively for classification between women with PCOS and healthy women. Expand
Polycystic ovary syndrome
TLDR
The diagnostic traits of polycystic ovary syndrome are hyperandrogenism, chronic anovulation, and poly Cystic ovaries, after exclusion of other conditions that cause these same features. Expand
Ovarian morphology and insulin sensitivity in women with bulimia nervosa
TLDR
Whether women with bulimia nervosa are insulin resistant and the relation between Insulin sensitivity and ovarian morphology is examined to examine. Expand
Hormonal and Biochemical Evaluation of Polycystic Ovary Syndrome
TLDR
Initial work-up of a patient with PCOS includes, at a minimum, thyroid-stimulating hormone, prolactin, and basal or stimulated 17(OH) progesterone levels to exclude thyroid dysfunction, hyperprolactinemia, and nonclassical congenital adrenal hyperplasia. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 38 REFERENCES
POLYCYSTIC OVARY SYNDROME: A CHANGING PERSPECTIVE
  • S. Franks
  • Biology, Medicine
  • Clinical endocrinology
  • 1989
TLDR
The article reports clinical and endocrine features in 300 women with PCOS, and discuses its etiology and the mechanism of anovulation. Expand
HETEROGENEITY OF THE POLYCYSTIC OVARY SYNDROME: CLINICAL, ENDOCRINE AND ULTRASOUND FEATURES IN 556 PATIENTS
TLDR
This paper reports an analysis of the clinical, endocrine and ultrasound data within a population of 556 patients with ultrasound‐diagnosed polycystic ovaries to illustrate the limitations in the use of specific clinical or endocrine criteria as requirements for the diagnosis of the poly Cystic ovary syndrome. Expand
Which is the Best Test to Detect the Polycystic Ovary?
  • J. Eden
  • Medicine
  • The Australian & New Zealand journal of obstetrics & gynaecology
  • 1988
TLDR
Overall, a biochemical ‘screen’ consisting of a luteinizing hormone (LH) level > 10 U/1, testosterone (T) >2.6nmol?/l, sex hormone binding globulin (SHBG) <31nmol/l or a FAI >4.5 was 89% sensitive and 98% specific for PCO, which is comparable with the reliability of ultrasound for detecting the PCO. Expand
REVIEW ARTICLE: THE POLYCYSTIC OVARY SYNDROME
TLDR
Current evidence regarding the basis for the dysfunction of ovarian steroidogenesis and follicular maturation, and the aberration of gonadotropin secretion as related to the inappropriate steroid feedback system will be reviewed. Expand
The diagnosis of polycystic ovaries in women with oligo‐amenorrhoea: predictive power of endocrine tests
TLDR
Assessment of oestrogen state is a useful method for categorizing patients with functional oligo‐amenorrhoea using ultrasonography as a reference test given the limited availability of the assay for SHBG. Expand
Obesity and Its Role in Poly cystic Ovary Syndrome
TLDR
When SSBG is lowered, there may be an increase in free T which, by inhibiting follicular maturation, may begin the sequence of events seen in polycystic ovary syndrome. Expand
Elevations in unbound serum estradiol as a possible mechanism for inappropriate gonadotropin secretion in women with PCO.
TLDR
Serum LH:FSH ratios had a positive correlation with the relative and absolute concentration of unbound E2, suggesting that IGS characteristically found in PCO patients and exemplified by elevated LH;F SH ratios, is the result of the feedback response to elevated levels of un bound E2. Expand
Hormonal studies on women with polycystic ovaries diagnosed by ultrasound.
TLDR
There is a relationship between the degree of hormonal abnormality and the menstrual irregularities and hirsutism in women with PCOS suggesting that there may be a progressive nature to the syndrome. Expand
The diagnosis of polycystic ovaries in subfertile women
TLDR
A group of subfertile women with PCO and regular cycles was found who had no other identifiable cause for their infertility and had higher follicular phase concentrations of LH and higher FAI than ovulatory women with normal ovaries. Expand
GLUCAGON IN WOMEN WITH POLYCYSTIC OVARY SYNDROME (PCO): RELATIONSHIP TO ABNORMALITIES OF INSULIN AND ANDROGENS
TLDR
It is concluded that glucagon is not implicated in peripheral insulin resistance in women with PCO and no other relationships were demonstrated between hormone values and those of glucagon in the other groups. Expand
...
1
2
3
4
...