Which Agent and how to Deliver it

  title={Which Agent and how to Deliver it},
  author={Rory F. McCloy and Russell C. Pearson},
Amnesia, relaxation, and cooperation, not anaesthesia, should be the clinical end points when using intravenous sedative drugs for endoscopic procedures. Diazepam has now been replaced by midazolam as the first-choice sedative agent to achieve these effects. Midazolam, when used in correct doses, is more suited to endoscopy than diazepam because of its shorter elimination half-life, larger volume of distribution, and faster total body clearance. Midazolam is also clinically superior, as it… CONTINUE READING


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