Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast

@article{Leadsham2009Whi2pLN,
  title={Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast},
  author={J. Leadsham and K. Miller and K. Ayscough and S. Colombo and E. Martegani and P. Sudbery and C. Gourlay},
  journal={Journal of Cell Science},
  year={2009},
  volume={122},
  pages={706 - 715}
}
Elucidating the mechanisms by which eukaryotic cells coordinate environmental signals with intracellular `fate' decisions, such as apoptosis, remains one of the important challenges facing cell biologists. It has recently emerged that the dynamic nature of the actin cytoskeleton is an important factor in the linkage of sensation of extracellular stimuli to signalling mechanisms that regulate programmed cell death. In yeast, actin has been shown to play a role in the regulation of apoptosis as… Expand
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